Sulfatides Inhibit Adhesion, Migration, and Invasion of Murine Melanoma B16F10 Cell Line <i>in Vitro</i>
نویسندگان
چکیده
منابع مشابه
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion.
Autotaxin (ATX) is a prometastatic enzyme initially isolated from the conditioned medium of human melanoma cells that stimulates a myriad of biological activities, including angiogenesis and the promotion of cell growth, survival, and differentiation through the production of lysophosphatidic acid (LPA). ATX increases the aggressiveness and invasiveness of transformed cells, and ATX levels dire...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2012
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.b12-00492